Brandon Mysliwiec Contact
PrecisePepResearch Library

Research information only. PrecisePep is an educational library. It is not medical advice and is not intended to assist, encourage or enable self-administration. The compounds documented here are research chemicals — most are not approved for human use. Read the full disclaimer.

Monographs

Peptide library

50 individual compounds. Each monograph separates study-reported findings from mechanistic inference and from uncontrolled community reports, states the study model on every claim, and links out to primary sources.

Metabolic & Adipose Regulation

5-Amino-1MQ

5-amino-1-methylquinolinium · NNMT inhibitor

Not a peptide at all — a small-molecule enzyme inhibitor that blocks NNMT in fat cells, raising intracellular NAD⁺ and, in mice, converting stored fat into burned…

NNMT inhibitorNAD⁺SIRT1 Open monograph →
Neuro-Cognitive & Nootropic

Adamax

adamantane-modified Semax analogue · adamantyl-Semax

A Semax analogue with an adamantane cage bolted on for enzymatic stability and membrane permeability. Reported as markedly stronger than the parent — on an eviden…

BDNFSemax analogueAdamantane Open monograph →
Metabolic & Adipose Regulation

AOD-9604

hGH fragment 176-191 · AOD9604

The C-terminal fragment of growth hormone, developed to deliver GH-like fat loss without GH-like side effects — which it achieved by delivering, in the pivotal hu…

hGH fragmentLipolysisFailed phase 2b Open monograph →
Immune & Anti-Inflammatory

ARA-290

cibinetide · Helix B surface peptide

An erythropoietin fragment that keeps EPO tissue-protective signalling and discards the blood-cell effect entirely — with genuine randomised human trial data in s…

EPO-derivedInnate repair receptorNeuropathy Open monograph →
Regenerative & Tissue Repair

BPC-157

Body Protection Compound-157 · PL 14736

A 15-amino-acid fragment of a gastric protective protein with an unusually broad pre-clinical healing literature — and an unusually thin human one. The gap betwee…

AngiogenesisVEGFR2Tendon Open monograph →
Metabolic & Adipose Regulation

Cagrilintide

AM833 · Cagri

A once-weekly amylin and calcitonin receptor agonist that works on satiety circuits incretins do not touch — which is precisely why it is being developed as a par…

AmylinCalcitonin receptorOnce-weekly Open monograph →
Growth Hormone & Anabolic Support

CJC-1295 (no DAC)

Mod GRF(1-29) · Modified GRF 1-29

A GHRH fragment with four amino-acid substitutions for enzymatic stability — engineered to last long enough to work and short enough to still produce a pulse. The…

GHRH analogueNo DACPulsatile Open monograph →
Endocrine & Reproductive Axis

Desmopressin

DDAVP® · Nocdurna®

Vasopressin with the blood-pressure effect engineered out and the water effect left in — two small changes to a nine-residue hormone that turned a vasoconstrictor…

Vasopressin analogueV2-selectiveDiabetes insipidus Open monograph →
Neuro-Cognitive & Nootropic

DSIP

delta sleep-inducing peptide · emideltide

Named for an effect it has never reliably reproduced — a nonapeptide isolated from sleeping rabbits in the 1970s, and the one compound the FDA advisory committee …

SleepNonapeptideInconsistent evidence Open monograph →
Metabolic & Adipose Regulation

Dulaglutide

Trulicity® · LY2189265

A GLP-1 agonist fused to an antibody fragment rather than acylated — the one whose cardiovascular trial was run largely in people who had not yet had an event, an…

GLP-1Fc fusionWeekly Open monograph →
Immune & Anti-Inflammatory

Enfuvirtide

Fuzeon® · T-20

A 36-residue peptide that blocks HIV from fusing with the cell it is trying to enter — the largest peptide drug in this library, the first entry inhibitor ever ap…

Fusion inhibitorHIV36 residues Open monograph →
Longevity & Circadian

Epitalon

Epithalon · Ala-Glu-Asp-Gly

A four-residue pineal bioregulator with the boldest claim in the field — telomerase induction and telomere elongation in human somatic cells — resting almost enti…

TelomerasePinealMelatonin Open monograph →
Metabolic & Adipose Regulation

Exenatide

Byetta® · Bydureon®

The first GLP-1 agonist ever approved, and not a human peptide at all — it comes from the venom of a lizard, and it is the reason this entire drug class exists.

GLP-1Exendin-4First in class Open monograph →
Regenerative & Tissue Repair

GHK-Cu

Glycyl-L-histidyl-L-lysine copper(II) · copper peptide

An endogenous copper-binding tripeptide with a real human topical evidence base, a large gene-expression literature, and one property no other repair peptide has:…

CollagenECM remodellingCopper Open monograph →
Immune & Anti-Inflammatory

Glutathione

GSH · γ-glutamyl-cysteinyl-glycine

The master antioxidant — a tripeptide every cell already synthesises for itself, sold for injection despite an oral precursor being cheaper, better studied and ar…

AntioxidantPhase II detoxTripeptide Open monograph →
Mitochondrial & Bioenergetic

Humanin

HN · HNG (potent analogue)

The first mitochondrial-derived peptide ever identified — discovered in a search for what protects surviving neurons in Alzheimer brains, and still almost entirel…

Mitochondrial-derivedCytoprotectiveSTAT3 Open monograph →
Growth Hormone & Anabolic Support

IGF-1 LR3

Long R3 IGF-1 · LR3

An engineered IGF-1 analogue designed to escape the binding proteins that normally regulate it — which is precisely why it is potent, and precisely why it is the …

IGF-1 analogueBinding-protein evasionHypoglycaemia risk Open monograph →
Metabolic & Adipose Regulation

Insulin & analogues

human insulin · insulin glargine

The foundational peptide therapy, and the only compound in this library that reliably kills people through ordinary dosing error. It is here for completeness and …

FoundationalPrescription onlySevere hypoglycaemia risk Open monograph →
Growth Hormone & Anabolic Support

Ipamorelin

NNC 26-0161 · Aib-His-D-2-Nal-D-Phe-Lys-NH₂

The first genuinely selective growth hormone secretagogue — a pentapeptide that releases GH without the cortisol, prolactin and hunger surge that made earlier ghr…

GHS-R1aGhrelin mimeticSelective Open monograph →
Endocrine & Reproductive Axis

Kisspeptin-10

KP-10 · metastin(45-54)

The master switch upstream of the entire reproductive axis — the signal that starts puberty, and one of the few compounds here with a genuine and active human res…

KISS1R / GPR54GnRHLH pulsatility Open monograph →
Immune & Anti-Inflammatory

KPV

Lys-Pro-Val · α-MSH (11–13)

The three-residue business end of alpha-MSH — an anti-inflammatory tripeptide that suppresses NF-κB from inside the cell, without the pigmentation and erectile ef…

NF-κBAnti-inflammatoryGut Open monograph →
Hormone Suppression & Oncology

Leuprolide

Lupron® · Lupron Depot®

A GnRH analogue that shuts the reproductive axis down by overstimulating it. Given continuously instead of in pulses, the same signal that starts puberty ends it …

GnRH agonistProstate cancerEndometriosis Open monograph →
Gastrointestinal & Mucosal

Linaclotide

Linzess® · Constella®

A 14-residue peptide that is swallowed rather than injected, is not meant to be absorbed, and works entirely on the luminal surface of the gut it passes through. …

Oral peptideGC-C agonistIBS-C Open monograph →
Metabolic & Adipose Regulation

Liraglutide

Victoza® · Saxenda®

The daily GLP-1 agonist that proved the class could reduce cardiovascular death — now superseded on potency, and still the agent with the most randomised evidence…

GLP-1DailyFDA approved Open monograph →
Immune & Anti-Inflammatory

LL-37

cathelicidin antimicrobial peptide · CAP-18 fragment

The only antimicrobial peptide the human body makes in the cathelicidin family — a direct bacterial killer that is also a powerful immune signal, and whose biolog…

AntimicrobialCathelicidinBiofilm Open monograph →
Aesthetic & Melanocortin

Melanotan-2

MT-2 · MT-II

A non-selective melanocortin agonist that tans skin, suppresses appetite and causes erections — because it hits four receptors at once and cannot be told which on…

MC1RMC4RTanning Open monograph →
Mitochondrial & Bioenergetic

MOTS-c

Mitochondrial ORF of the 12S rRNA type-c · mitochondrial-derived peptide (MDP)

A 16-residue peptide encoded in mitochondrial DNA that travels to the nucleus under metabolic stress and rewrites the transcriptional response — an exercise-mimet…

AMPKInsulin sensitivityExercise mimetic Open monograph →
Mitochondrial & Bioenergetic

NAD⁺

nicotinamide adenine dinucleotide · NAD+

Not a peptide — a coenzyme every cell already depends on. The interesting question is not whether it matters, which is settled, but whether injecting it does anyt…

CoenzymeSirtuinsPARP Open monograph →
Hormone Suppression & Oncology

Octreotide

Sandostatin® · Sandostatin LAR®

The mirror image of everything else in the growth-hormone section of this library. Eight residues that suppress GH rather than release it — and the drug that made…

Somatostatin analogueAcromegalyNeuroendocrine tumours Open monograph →
Metabolic & Adipose Regulation

Orforglipron

Foundayo® · LY3502970

Not a peptide — and that is the entire reason it matters. The first oral small-molecule GLP-1 receptor agonist approved for weight management, made in a chemical …

OralSmall moleculeGLP-1 Open monograph →
Endocrine & Reproductive Axis

Oxytocin

Pitocin® · Syntocinon®

Nine residues, two clinical lives, and one of the widest gaps in medicine between what a molecule reliably does and what the internet says it does. It empties a u…

UterotonicPostpartum haemorrhageIntranasal claims Open monograph →
Growth Hormone & Anabolic Support

PEG-MGF

pegylated mechano growth factor · IGF-1Ec

A splice variant of IGF-1 that muscle produces when mechanically damaged — pegylated to survive long enough to be injected, on the theory that supplying the signa…

IGF-1 splice variantSatellite cellsPegylated Open monograph →
Metabolic & Adipose Regulation

Pramlintide

Symlin® · pramlintide acetate

The only approved amylin analogue — the drug that proved beta-cell replacement needs two hormones, not one, and the reason every cagrilintide claim has a safety p…

Amylin analogueFDA approvedMealtime adjunct Open monograph →
Aesthetic & Melanocortin

PT-141

bremelanotide · Vyleesi®

The melanotan metabolite that became an approved drug — a centrally acting melanocortin agonist for sexual desire, working on the brain rather than on blood flow.

MC4RBremelanotideFDA approved Open monograph →
Metabolic & Adipose Regulation

Peptide YY (PYY)

PYY3-36 · peptide tyrosine tyrosine

The satiety hormone the gut releases after a meal — a genuine target with a genuine development history, and a nasal formulation that failed on nausea so badly it…

Y2 receptorSatietyNausea-limited Open monograph →
Metabolic & Adipose Regulation

Retatrutide

LY3437943 · Reta

An investigational once-weekly triple agonist at the GLP-1, GIP and glucagon receptors — currently the most weight-effective single molecule in published obesity …

GLP-1GIPGlucagon Open monograph →
Neuro-Cognitive & Nootropic

Selank

Thr-Lys-Pro-Arg-Pro-Gly-Pro · tuftsin analogue

A tuftsin analogue registered in Russia as an anxiolytic — reported in domestic clinical work to match benzodiazepines for anxiety without sedation, dependence or…

AnxiolyticGABABDNF Open monograph →
Metabolic & Adipose Regulation

Semaglutide

Ozempic® · Wegovy®

The GLP-1 agonist that started the current era — and the only compound in this class with cardiovascular outcome data, kidney outcome data and a decade of post-ma…

GLP-1FDA approvedOnce-weekly Open monograph →
Neuro-Cognitive & Nootropic

Semax

Met-Glu-His-Phe-Pro-Gly-Pro · ACTH(4-7)-PGP

A Russian ACTH(4-7) analogue stripped of hormonal activity and registered in Russia as a nootropic and stroke medicine — with a large Russian-language clinical li…

BDNFNootropicIntranasal Open monograph →
Growth Hormone & Anabolic Support

Sermorelin

GHRH(1-29) · Geref®

The original GHRH fragment — once an FDA-approved diagnostic and paediatric growth agent, withdrawn commercially rather than for safety, and now the most compound…

GHRH(1-29)Formerly approvedVery short half-life Open monograph →
Metabolic & Adipose Regulation

SLU-PP-332

ERR agonist · oestrogen-related receptor pan-agonist

A small molecule that switches on the transcriptional programme endurance exercise produces — the closest thing to a genuine exercise mimetic in this catalogue, a…

ERR agonistExercise mimeticSmall molecule Open monograph →
Mitochondrial & Bioenergetic

SS-31

Elamipretide · MTP-131

A cardiolipin-binding tetrapeptide that concentrates thousands-fold inside mitochondria and restores cristae architecture — the most clinically advanced mitochond…

CardiolipinCristaeATP Open monograph →
Regenerative & Tissue Repair

TB-500

Thymosin β4 fragment · Tβ4 (17–23) acetylated fragment

A synthetic fragment marketed as thymosin beta-4 — actin-binding, cell-migration-promoting, anti-fibrotic in pre-clinical work, and routinely conflated with the f…

ActinCell migrationAnti-fibrotic Open monograph →
Gastrointestinal & Mucosal

Teduglutide

Gattex® · Revestive®

The incretin nobody talks about. GLP-2 comes from the same precursor gene as GLP-1 but grows intestine rather than suppressing appetite — and the drug built from …

GLP-2Short bowelMucosal growth Open monograph →
Bone & Skeletal

Teriparatide

Forteo® · Bonsity®

The first drug that built bone rather than slowing its loss — a 34-residue fragment of parathyroid hormone that works only because it is given intermittently. Con…

PTH analogueAnabolicOsteoporosis Open monograph →
Endocrine & Reproductive Axis

Terlipressin

Terlivaz® · Glypressin®

A vasopressin prodrug that constricts the splanchnic circulation for hours from a single injection — the first drug ever approved in the United States for hepator…

Vasopressin analogueV1-preferringHepatorenal syndrome Open monograph →
Growth Hormone & Anabolic Support

Tesamorelin

TH9507 · Egrifta®

A stabilised growth-hormone-releasing hormone analogue and the only FDA-approved drug that specifically targets visceral adipose tissue — approved for one narrow …

GHRH analogueVisceral fatFDA approved Open monograph →
Metabolic & Adipose Regulation

Tesofensine

NS2330 · triple monoamine reuptake inhibitor

A triple monoamine reuptake inhibitor that failed as a Parkinson drug and turned out to cause substantial weight loss — a centrally acting stimulant, not a peptid…

Monoamine reuptakeStimulantSmall molecule Open monograph →
Immune & Anti-Inflammatory

Thymosin Alpha-1

Tα1 · thymalfasin

A thymic peptide approved as a medicine in more than thirty countries for hepatitis B and C — one of the few compounds in this library with a genuine internationa…

T-cellTLRImmune modulation Open monograph →
Metabolic & Adipose Regulation

Tirzepatide

LY3298176 · Mounjaro®

The dual GIP/GLP-1 agonist that reset expectations for obesity pharmacology — approved, extensively trialled, and the only compound in this class on this site wit…

GLP-1GIPFDA approved Open monograph →
Blends & stacks →